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In the trial, 143 subjects with acute exacerbations of chronic bronchitis were treated with 250 mg of cefuroxime axetil twice daily and 153 subjects received 250 mg of amoxicillin three times daily. Results showed that 76. In clinical trials of cefuroxime axetil, patients who received 7-10 days of therapy experienced adverse reactions similar in type and frequency to those of other antibiotic agents.
The agent has been available in the Untied States since 1992 and is also marketed in Italy, Spain, and the United Kingdom. The product is expected to have patent protection until 2006 in the United States and for a period ranging from 2004 to 2008 in the European markets. Cefprozil is active against gram-positive and gram-negative bacteria, but not Pseudomonas species.
In clinical studies, this cephalosporin was proven active against S. In vitro tests have shown cefprozil is also effective against a variety of other bacteria, including streptococci and gram-negative microbes. In clinical trials for cefprozil, side effects included nausea, diarrhea, vomiting, and abdominal pain. Sankyo originally developed cefpodoxime proxetil and first launched the cephalosporin in Japan in 1989. A generic version of the product oral suspension and tablets by Ranbaxy is available in the United States. Cefpodoxime is indicated for the treatment of acute exacerbations of chronic bronchitis caused by S.
Clinical studies have shown cefpodoxime to be active against S.
Cefuroxime Axetil. Cefprozil. Cefpodoxime Proxetil
Additionally, a dosage of 100 mg or 200 mg of cefpodoxime twice daily demonstrated similar clinical and bacteriological efficacy to amoxi-cillin received in 250 mg doses three times daily. In clinical trials, cefpodoxime is well tolerated; patients reported experiencing nausea 3. Dosage forms of Cefuroxime: